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<p class="MsoNormal"><span style="font-size:11.0pt">Ka Hei Lui, Xinye Zhu, Yik-Sze Lau, Tianhang Zhang, Gehui Wang, Hsiao-Chi Chuang, Kin Fai Ho, Characterization of chemical and bioreactivity properties of photooxidation reaction products from secondary organic
aerosols (SOA) under high OH exposure condition, Atmospheric Environment, 2025, 121212,
<a href="https://doi.org/10.1016/j.atmosenv.2025.121212">https://doi.org/10.1016/j.atmosenv.2025.121212</a>, 2025. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt">Abstract</span></b><span style="font-size:11.0pt">: The chemical and bioreactivity properties of photooxidation products emitted during high radical exposure conditions were characterized. The purpose was
to simultaneously investigate the influences of the toxicity of photooxidation products from common anthropogenic and biogenic precursors (toluene, m-xylene and isoprene). The major ring-opening compounds were identified as pyruvic acid (C3H4O3), glyceric
acid (C3H6O4), succinic acid (C4H6O4), malic acid (C4H6O5), tartaric acid (C4H6O6), 2,3-dihydroxy-glutaric acid (C5H8O6), glycolic acid (C2H4O3) and oxalic acid (C2H2O4) originated from the toluene and xylene-derived secondary organic aerosol (SOA) products
in the analysis. The average LDH level from isoprene-derived SOA (0.77 ėg/ml) was higher than the control (0.75 ėg/ml) and the DCFH level from isoprene-derived SOA (228.73 RFU) was also higher than the control (215.18 RFU). In addition, the average LDH level
from toluene-derived SOA (0.86 ėg/ml) was higher than the isoprene (0.77 ėg/ml). The IL-6 level from toluene-derived SOA (182.82 pg/ml) was higher than the xylene-derived SOA (173.00 pg/ml). These suggested enhanced cytotoxicity and cell membrane damage under
toluene-derived SOA exposure. The isoprene-derived SOA induced higher DCFH levels of (228.73 RFU), implying the potential effects of particulate matter from SOA on the oxidative potential and rising cellular oxidant burden. The overall results suggest that
the oxidation products can potentially cause various cytotoxic effects. This finding warrants further investigation into the toxicity profiles of SOA and regulation of SOA pollution.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><a href="https://sites.google.com/site/pamwiki/publications-using-the-pam-oxidation-flow-reactor?authuser=0">PAM Wiki - Publications Using the PAM Oxidation Flow Reactor</a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-ligatures:none">Andrew Lambe<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-ligatures:none">Principal Scientist<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-ligatures:none">Aerodyne Research, Inc.
<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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